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KMID : 0829220190430050171
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Korean Journal of Oral and Maxillofacial Pathology
2019 Volume.43 No. 5 p.171 ~ p.178
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The Effect of Natural-Herb Mixture Extract on Osteogenic Differentiation in Human Mesenchymal Stem cells
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Kim Da-Sol
Seong Ki-Soo
Park Min-Sung
Kim Mi-Kyoung
Park Kyoung-Eun
Kwak Yeon-Ju
Youn Geum-Joung
Kim Hyung-Joon
Bae Moon-Kyung
Bae Soo-Kyung
Jang Hye-Ock
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Abstract
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Herbal medicine has been the basis for medical treatments through much of human history, and such traditional medicine is still widely practiced today. Modern medicine makes use of many plant-derived compounds as the basis for pharmaceutical drugs. In traditionally, Achyranthes aspera, Safflower (Carthamus tinctorius) seed and Acanthopanax senticosus have been used for the treatment and prevention of bone-related diseases. In this study, we investigated the pharmacological effect of mixture of Achyranthes aspera, Safflower (Carthamus tinctorius) seed and Acanthopanax senticosus and the other herbs. Two types of enzymes were used to enhance the extraction components of amino acid, mineral content, free sugar, and flavor recovery in extracting natural herbal mixtures(NME).
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KEYWORD
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NME extract, Human bone-marrow mesenchymal stem cells, Osteogenic differentiation, APA
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